Lions vs Eagles Week 11 Preview: Early Picks, Odds, and Game Outlook for Sunday Night Football

The Week 11 Sunday Night Football matchup presents one of the most tantalizing games of the 2025 NFL season so far, as the Philadelphia Eagles host the Detroit Lions at Lincoln Financial Field in Philadelphia. With playoff implications looming, this game could serve as a preview of a potential NFC Championship showdown, making it must-watch primetime football.

Early Predictions and Betting Lines

Early betting odds favor the Philadelphia Eagles by a narrow spread of -1.5 points, with moneyline odds positioning the Eagles as slight favorites (-125) over the Lions (+105). The over/under total has been set around 48.5 points, hinting at a moderately scoring game.

While the Eagles are favored on their home turf, the Lions come in with momentum after an impressive 44-22 victory over the Washington Commanders in Week 10. Detroit has demonstrated resilience and tactical discipline, especially since Dan Campbell took on play-calling duties last week. Despite the Eagles’ short rest following a Monday night game against the Green Bay Packers, their adaptability and strong defense make them a formidable opponent.

Why the Eagles Are Slight Favorites

The Eagles are arguably the most adaptable team in the NFL right now. They can control the pace with a physical running game or exploit a weaker secondary with an efficient passing attack. Their defense was outstanding against the Packers, limiting Green Bay to just 4.0 yards per play. The Eagles’ revived pass rush has been a game-changer in their three-game winning streak, with 10 sacks and increasing pressures on opposing quarterbacks, thanks in part to key players like Jaelan Phillips, who made a significant impact immediately after being acquired.

The Eagles’ defense is expected to once again challenge Lions quarterback Jared Goff, who has been under pressure frequently this season, ranking sixth in pressure rate among quarterbacks. Goff’s quick-hitting passing style helps mitigate this, but the pressure will likely dictate the pace of the game. With Jalen Hurts’ dual-threat capability leading the Eagles, expect Philadelphia to test the Lions’ defense with a balanced attack.

Lions’ Strength and Momentum

Detroit has been climbing the NFC North standings with a 6-3 record and a dominant performance in Week 10. The Lions’ offensive line zeroed in on protecting Goff, allowing no sacks and facilitating an efficient offensive attack that resulted in touchdowns on all seven possessions. Their running back Jahmyr Gibbs continues to prove his star status, rushing for 142 yards and scoring multiple touchdowns against Washington. Gibbs joins an exclusive group of historic players with over 40 career touchdowns before turning 24.

Goff has also been impressive with a league-leading 74 percent completion rate this season. The Lions offense, under Dan Campbell's direct play-calling, has increased its rushing attempts (48.5% of plays run), a strategy designed to keep the clock moving and the Eagles defense on the field. This style could result in a lower-scoring game, which aligns with predictions leaning toward the total falling under 48.5 points.

Key Defensive Matchups

Philadelphia’s defense, led by coordinator Vic Fangio, prioritizes run defense and has been effective overall, though the Eagles have struggled at times to contain strong rushing attacks, ranking 24th in rush defense DVOA prior to their recent win over Green Bay. Safety Jalen Carter’s presence has been a critical factor in improving their run defense, as the Eagles have not allowed a 100-yard rusher while Carter has been in the lineup this season.

Detroit’s offense will seek to exploit these vulnerabilities, especially with the Lions ranking sixth in rush offense DVOA. If their offensive line can maintain the performance seen against Washington, Detroit’s running game will challenge the Eagles’ front seven.

On the flip side, the Eagles’ defensive front has regained dominance, with emerging pass rushers such as Jaelan Phillips and Nolan Smith pressuring QBs effectively. The Lions’ offensive line will be tested significantly as Philadelphia looks to disrupt Goff’s rhythm.

Recent Team Performances

The Eagles come off a hard-fought 10-7 victory over the Packers on Monday Night Football. The game was a defensive showcase with limited scoring until a late touchdown pass from Hurts to DeVonta Smith provided the winning margin. The Eagles’ ability to hold Jordan Love and the Packers offense in check was a testament to their defensive discipline and preparation.

The Lions, meanwhile, exploded in Week 10 with a 44-22 win over the Commanders. The dominant offensive line and the explosive playmaking from players like Gibbs and receiver Jameson Williams—who averaged nearly 20 yards per reception—highlight the Lions’ offensive potential.

What to Expect on Sunday Night

Given the close odds and contrasting styles, expect a strategic, physically intense game. The Eagles will likely try to manage the clock and leverage their defense to limit big plays from Detroit. The Lions, energized by their recent success, will look to control the ground game and exploit any openings in Philadelphia’s defense.

The total points may lean slightly under the posted lines, considering the defensive prowess displayed by both teams and the Lions’ tendency for a run-heavy offense under Campbell’s play-calling.

How to Watch

• Date: Sunday, November 16, 2025

• Time: 8:20 p.m. ET

• Location: Lincoln Financial Field, Philadelphia, PA

• Broadcast: NBC

  
  

Final Thoughts and Betting Tips

The early line favors the Eagles by a small margin, but there's legitimacy in considering the Detroit Lions, especially on the moneyline given their strong recent form and underdog trend under Dan Campbell. Waiting until closer to game day to see the impact of any injury updates and betting trends is advisable.

For totals, lean towards the under as defensive adjustments and a run-heavy approach could keep the scoring in check, with the total likely settling between 47 and 48 points.

This Week 11 SNF game promises playoff-intensity football, high stakes, and compelling narratives as two NFC powerhouses clash in a critical midseason showdown.