NFL Week 10 Injury Report & Waiver Projections
- Football Nation
- 4 days ago
- 3 min read
NFL Week 10 Injury Report & Waiver Projections: Fantasy Football Outlook
By Week 10 of the 2025 NFL season, injuries have derailed several stars and reshaped fantasy rosters across every position. As trade deadlines approach and fantasy playoffs near, managers must balance recovery timelines, replacement value, and schedule analysis to stay competitive. Below is the most valuable breakdown of current injury updates and waiver projections heading into the week.
Quarterbacks
Jayden Daniels, Commanders (Elbow)Daniels sustained a dislocated elbow late against Seattle and is expected to miss extended time. His dual-threat upside leaves a major void for Washington and for fantasy managers. Marcus Mariota takes over as starter and becomes a viable streaming QB2 option given his past production (averaging 18.7 fantasy points in games with over 50% snaps).
C.J. Stroud, Texans (Concussion)Stroud remains in concussion protocol with Davis Mills likely starting versus Jacksonville. Expect a downgrade to Houston’s offensive ceiling, particularly for Nico Collins and Tank Dell. Mills carries desperation streaming value in superflex formats only.
Brock Purdy, 49ers (Toe)Limited practice early in the week. Monitor closely; Sam Darnold would step in if Purdy experiences setbacks but would face a tough Ravens defense.
Waiver Target – Marcus Mariota (5% rostered, $1 FAB)If Daniels’ setback extends beyond Week 10, Mariota offers mid-tier streaming reliability against Detroit. His rushing floor still provides QB2 insurance.
Running Backs
Aaron Jones Sr., Vikings (Shoulder)Suffered an AC joint sprain, expected to be day-to-day. Jones looked explosive prior to exiting, but age and durability remain concerns. If he sits, Jordan Mason profiles as RB1-caliber workload replacement.
Quinshon Judkins, Browns (Shoulder)Judkins’ AC joint sprain status hinges on practice participation. Rookie Dylan Sampson remains a priority stash with RB3 value if Judkins doesn’t play.
Ollie Gordon II, Dolphins (Ankle)Missed time with an ankle issue. Monitor his midweek practice logs. In deeper formats, Ray Davis remains an upside hold.
Trending Waiver Targets:
Dylan Sampson, Browns (16% rostered, $4 FAB): Could inherit feature-back duties if Judkins sits.
Tank Bigsby, Eagles (26% rostered, $3 FAB): Productive fill-in if Barkley’s groin injury delays return.
Bhaysul Tuten, Bears (31% rostered, $3 FAB): Emerging as a flex option due to favorable usage in space.
High-Upside Stashes: Ray Davis (8%), Devin Neal (3%)
Wide Receivers
Brian Thomas Jr., Jaguars (Ankle) – Day-to-day following Week 9 exit.
Puka Nacua, Rams (Ribs) – Expected to play through pain but risk of limited snaps.
Kayshon Boutte, Patriots (Hamstring) – Limited range of motion; unlikely to play.
A.J. Brown, Eagles (Hamstring) – Slight tightness; expected to be monitored through Thursday.
Top Waiver Adds:
Alec Pierce, Colts (26% rostered, $3 FAB): Averaging 83 yards over last three games, with growing chemistry in an elite passing offense. WR3/flex in PPR leagues.
Tory Horton, Seahawks (5% rostered, $2 FAB): Capitalized on Cooper Kupp’s absence with 48 yards and two TDs. Holds WR4/flex value until Kupp returns.
Parker Washington, Jaguars (18% rostered, $2 FAB): 12 catches for 142 yards over last two games. Gains short-term starting volume amid Jacksonville’s injury depletion.
Dart Throws & Deep League Flyers:Dyami Brown (if cleared from concussion), Tez Johnson vs. NE, Troy Franklin vs. LV
Tight Ends
Cole Kmet, Bears (Concussion)Out indefinitely until cleared; rookie Colston Loveland’s breakout could cement his elevated target share.
Tucker Kraft, Packers (ACL)Confirmed out for the season. Luke Musgrave inherits primary duties in Green Bay’s offense, though target share remains volatile.
Top Waiver Adds:
Colston Loveland, Bears (24% rostered, $5 FAB): Exploded for 118 yards and two TDs. Strong TE1 streamer regardless of Kmet’s status.
Harold Fannin Jr., Browns (near 50% rostered): Must-roster if available; steady red zone usage.
Mason Taylor, Bengals (20% rostered): Sneaky TE2 streamer if Perine remains sidelined.
Upside Stashes: Terrance Ferguson (0%), Juwan Johnson (35%)
Defense/Special Teams Streamers
Kickers to Add
Fantasy Strategy Notes
Injury volatility is peaking; stash handcuffs for all top-20 RBs.
Rookie WRs (Pierce, Washington, Horton) offer high target efficiency with room to grow as injuries mount.
Prefer TE streaming with weekly upside rather than name recognition; Loveland and Fannin are the current gold standards.
Keep an eye on post-trade-deadline usage shifts, especially among Jacksonville, Seattle, and Green Bay receiving corps.